I just discovered Leatherworker.net recently, after a friend of mine mentioned that he has several elk hides that have been sitting around just waiting for a project (he dreams of having a coat made from the hides...) Well, I've been sewing FABRIC for many years & have made coats, and lots of costumes - including "Neo & Trinity" from the Matrix. Neo's jacket was from black denim, and Trinity was from Lycra-backed vinyl (it's stretchy, but icky synthetic that after 16 years has finally gotten sticky so it can't be worn any longer).
As far a leatherwork, I've done a bit of hand-stitching with real leather, made purse handles with pleather (fake leather) & sewn a suede purse (pigskin). I really enjoyed making the purse and found that I prefer using real leather over the pleather. The only advantage of the pleather is that it's far less expensive than real leather - but once you try real leather, you just don't want to go back to the fake stuff. I'm currently working on a project that's using synthetic suede and am sewing it on my trusty antique Singer 201. I love that machine, but since it's a home-sewing machine, I don't want to throw at it anything thicker than 3oz leather. My friend's elk hide is 3 - 6 oz, so some of it will be OK, but I fear that the irregularities in thickness will kill my antique Singer once the number of layers builds up. I'm drooling over some of the spiffy leatherworking machines, but haven't decided which yet.
The attached photos are of the purse. It's small - about 6x9" - but a good size for my use. One side has two seams and the other has one because the purse was a "sampler" in which I tried out various leather seaming techniques. Because the pigskin suede was garment-weight (about 2 oz), my Singer 201 sewed it about as easily as any home machine handles quilting cotton.