If you mean OSB, then yeah, but that wouldn't last in the weather. I set up my cut station outside most of the time. When I get a chance to travel to Dallas maybe I can snag a sheet or two of MDO.
In the meantime, here are may tables I built.
Here is the pine table I built with dowel and pocket holes. We stained this one and put a piece of leathered finish fantasy brown granite on it.
Here is the oak table with m&t construction, linseed oil and quartz top.
I used half inch ply for both bottom shelves. And both are within a ⅛ of square across the tops of the frames on diagonal.
Enjoy.