YINTX is right, hand stitching looks better than most machine stitching but the most important thing is will you get a return on your investment of a sewing machine.
I just make a few pieces for sale and have had a lot of luck telling people it's hand stitched. They seem to think its worth more because I take the extra time and effort.
But if you are doing volume, a machine is probably the way to go. Again, some people will like the fact that you used a machine and think the stitching is superior.
Catch 22.